The new show is a high-stakes cash game that will feature $200/$400 No-Limit Hold'em with a $100,000 buy-in.
According to PokerStars some of the top poker players in the world will be invited including Daniel Negreanu.
In a new twist PokerStars will allow select qualifiers from the site to play in the Big Game.
The site is running qualifiers for the event and players in the US and Canada can play in free Big Game Round 1 qualifiers from now until June 25.
Winners will qualify for the Big Game final where the top 200 players will be invited to send PokerStars a casting video.
The players who are selected will be flown out and staked for $100,000 in the game by PokerStars. Whatever profit they make over $100,000 they will be allowed to keep.
No stranger to TV, PokerStars introduced the Million Dollar Challenge last year and is also sponsoring the "Did You Know" segment in the current season of High Stakes Poker.
High stakes cash games have become a popular format for poker TV shows and Poker After Dark, which is usually a six-player Sit and Go, recently added a $50,000 buy-in cash game episode to its schedule.
PokerStars has yet to announce when the show will be aired but the Big Game qualifiers can already be found in the poker room's lobby.