Except for a brief moment heads-up when Frenchman Guillaume Cescut took the lead, Homann went wire-to-wire for the win, entering the final table with a chip lead he grabbed on the event's first day.
The win more than doubled Homann's $183,537 in career live tournament earnings.
The World Poker Tour Marrakech presented by Chilipoker drew 222 players to the Casino De Marrakech at the Es Saadi Gardens & Resort in Morocco this week.
The victory also secured Homann a seat in the 2011 World Poker Tour Championship at Bellagio in Las Vegas this May.
Next up for the WPT is the annual Five Diamond World Poker Classic at Bellagio Dec. 3-8.
Here's how the final table finished up in Marrakech:
1 Sebastian Homann €244,508
2 Guillaume Cescut €135,831
3 Sebastien Compte €90,554
4 Felix Oberauer €72,439
5 Guillaume de la Gorce €54,334
6 Dominik Nitsche €36,220
7 Johan Williamsson €28,977
8 Julien Labussiere €25,356
9 Patrick Muleta €19,920